PERTH, Wash.—Researchers compared the effects of four protein meals—whey, tuna, turkey and egg albumin—on post-meal glucose and insulin concentrations, as well as on appetite measures and energy intake in 22 lean, healthy men (Br J Nutr. May 11, 2010). "There was a strong relationship between self-rated appetite, post-meal insulin response and energy intake at lunch. Whey protein meal produced a greater insulin response, reduced appetite and decreased ad libitum energy intake at a subsequent meal compared with the other protein meals, indicating a potential for appetite suppression and weight loss in overweight or obese individuals," researchers said.

The cross-over design study randomized participants to consume four liquid test meals on separate occasions and followed up with regular blood sample collections. Participants were then offered a buffet meal four hours later. The blood glucose response after the consumption of the test meal, as an incremental area under the curve (AUC), was significantly lower with the whey meal than with the turkey (P<0.023) and egg (P<0.001) meals, but it was not lower than with the tuna meal (P<0.34). The AUC blood insulin after the consumption of the test meal was significantly higher with the whey meal than with the tuna, turkey and egg meals (all P<0·001). The AUC rating of hunger was significantly lower with the whey meal than with the tuna (P<0.033), turkey (P<0.001) and egg (P<0.001) meals. Mean energy intake at the ad libitum meal was significantly lower (P<0.001) with the whey meal than with the tuna, egg and turkey meals.

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