Written by Bryan Hildebrand, Senior Editor
31 August 2021









Highly Anabolic Prohormone


1-Testosterone™ works to create the perfect anabolic environment for unbelievable gains in lean muscle mass and strength that will not disappear when your cycle is completed.


1-Testosterone™ by Hi-Tech Pharmaceuticals is based upon a naturally occurring metabolite that has properties far different from standard testosterone in the body. One of those is 1-androstene-3b-ol-17-one and is known in the bodybuilding community as 1-androsterone. Hi-Tech Pharmaceuticals saw the opportunity to fully develop 1-A with its proprietary Cyclosome™ Delivery system, which is more than just a fancy trademark. It’s what separates all prohormones and test boosters from any of the others. It provides an unparalleled increase bioavailability for gains never seen before.


In a study released in the Journal of Applied Physiology, the oral prohormone 1-androstene-3b-ol-17-one, which converts in the liver to 1-testosterone, was viewed as potent “milligram-for-milligram” to Testosterone Enanthate, the gold standard for Testosterone products. Very few dietary supplements have been subjected to clinical studies due to the overwhelming cost and FDA approval process. However, the active prohormone 1-androstene-3b-ol-17-one was the subject of a clinical study at the West Texas A&M University, the California Baptist University and the University of Texas at Austin. The results showed 1-androstene-3b-ol-17-one to be significantly more powerful than it would appear structurally.


In this study, the nine men tested gained an average lean mass of 10.4 pounds and an increase in strength of 92.2 pounds in total load on bench/squat/deadlift. These are deemed significant gains from an over-the-counter prohormone. Researchers concluded that the prohormone supplement contributed to robust improvements in muscle mass and strength via resistance training. Although additional and larger studies are necessary to substantiate the efficacy of any compound, it’s safe to say that 1-androstene-3b-ol-17-one’s abilities exceeded everyone’s expectations.


1-Testosterone™ provides clean gains that are very dry and lean in nature. This means you won’t get a lot water retention or estrogen activity with this prohormone. The lack of estrogen allows the ability to confidently stack this prohormone with 4-andro or another “wet” compound. This helps potentiate the gains and increase the comfort of the cycle. 1-Testosterone™ is used as the base for a multitude of stacks with the newest advances in prohormone abilities.


1-testosterone has a structure similar to testosterone, but the double bond is in a different place making the molecule subject to differing metabolism than standard testosterone. It cannot be converted to estrogen via aromatase nor can it be turned into DHT. This makes it a very stable molecule and resists most traditional routes of metabolism. A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized. Probably even more importantly, 1-testosterone has an anabolic to androgenic ratio of 200/100, which is superior to naturally occurring testosterone in men.


Bodybuilders, fitness enthusiasts and athletes pay attention. The muscle-building breakthrough of the 21st century is here, and the results being achieved by 1-Testosterone™ have been nothing short of phenomenal. 1-Testosterone™ works to create the perfect anabolic environment for unbelievable gains in lean muscle mass and strength that will not disappear when your cycle is completed.


With the proprietary oral delivery system in Cyclosome™ Technology, Hi-Tech Pharmaceuticals is changing how well your body will be able to utilize compounds. Cyclosome™ is a one-of-a-kind technology that involves the entrapment of hydrophobic compounds in the form of water-soluble cyclodextrin (CD) complex in liposomes. What does that mean? In short, you can think of Cyclosome™ in terms of a “Trojan horse,” passing through the liver unharmed and intact.


This new Cyclosome™ Technology allows the delivery of a wide array of ingredients to the systemic circulation by the intestinal lymphatic route, circumventing first-pass inactivation in the liver for the very first time. The pharmaceutical industry has embraced this cutting-edge technology in recent years and Hi-Tech Pharmaceuticals is introducing it in hard to deliver prohormones and test boosters to further expand bioavailability.


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1-Testosterone 60Ct Bottle New