Written by Bruce Kneller
08 April 2007

Methylated prohormones are all the rage now and why shouldn't they be? They work. They work better than anything we've ever seen. In some cases, they work better than "the real stuff." I know the infamous and inevitable "ban" on virtually all prohormones and prosteroids is just visible on the horizon, but until that happens, some companies and people (including yours truly) are really going to push it and launch some of the greatest supplements ever to see the light of day. So, I am going to talk about a new cool one today that goes by the names OxovarTM and Methoxabol.TM (These are the same thing, just different brand names for the same chemical). 

This new prosteroid is, indeed, a carbon 17 alpha-alkylated (methylated) goodie and boy is it one potent SOB. The actual chemical? 17a-methyl-4-hydroxy-19-nortesterone, also known by the acronymn "MOHN." This one is going to get confusing because this chemical is known by a variety of other names (in addition to the ones mentioned so far). I know having multiple names for chemicals is tough sometimes, but it keeps those idiots in congress who plan on banning these goodies thoroughly confused, which means it paralyzes them (albeit only for a short time), and that in turn means these things can be sold for longer periods of time. So it's a good thing- trust me on this. For the record, some of the other chemical names for OxovarTM/MethoxabolTM include: 

17a-methyl-3-oxo-19-norandrostene-4,17-diol

17a-methyl-3-keto-19-norandrostene-4,17-diol

17a-methyl-4-hydroxynandrolone

17a-methyl-4,17-dihydroxyestra-4-en-3-one

17a-methyl-3-oxo-estra-4-ene-4,17-diol

17a-methyl-3-keto-estra-4-ene-4,17-diol

Normethandrolone

 All of these are the exact same thing, just "spelled out" chemically a little differently.

             So, what makes MOHN so cool? Well, for starters, its effects are very similar to the infamous steroid Anavar (oxandroline), but it is about 10 times more anabolic than Anavar (oxandrolone). Yes, you read that correctly; OxovarTM/MethoxabolTM yields effects similar to Anavar (oxandrolone) but at much lower doses (six to nine milligrams per day total is all the MOHN you need). It is (at least on paper) somewhat androgenic and its A:A ratio is not much better than that of plain old testosterone (on paper), which is totally bizarre, because the few people lucky enough to try the first "samples" of MOHN pretty much had the same exact things to say about the effect it had:

1)    Easily the best pure strength/power/speed-building prosteroid out there today, bar none.

2)    Mediocre mass builder/mass gains.

3)    Accelerates fat loss better than any other prosteroid out there today, bar none.

4)    No decreased or increased effects on sex drive at effective dosages.

5)    Decreases joint pain much like Deca (nandrolone decanoate) is known to do.

6)    Does not aromatize; estrogenic and progestenic side effects not likely to be an issue.

7)    Can cause insane, freaky pumps and increases in vascularity; appears to be very angiogenic in nature.

8)    Nothing on the market will get you stronger/faster/harder in a short time frame than this stuff.

This is an excellent, high-tech prosteroid. OxovarTM/MethoxabolTM is truly the first methylated prosteroid primarily designed to increase athletic performance.  Much like Anavar (oxandrolone), baseball players, sprinters, football players, basketball players, heck, anyone looking to increase explosive power and strength without gaining a ton of size will love OxovarTM/Methoxabol.TM (You gain size with MOHN, there's no way around it, you just won't get the size from MOHN that you'd get from M1T or even Methyldienolone®). Being faster, quicker, stronger, able to jump higher, hit/throw further = the stuff that draws the attention of athletes. Right now, OxovarTM/MethoxabolTM is available via Gaspari Nutrition and Kilosports in capsules, and via Designer Supplements as an "oral liquid" that comes in an eye dropper gizmo.

Me? I prefer my goodies in caps and tabs. But others may not. Either way, this is the shiznit of performance enhancers. And it will shizzle your nizzle, so if you are interested in it, stock up on it before the market fizzle! Chemically, it's related to an obscure anabolic steroid that was never really popular in America called Oxabolone (4,17-dihydroxyestr-4-en-3-one or 4-hydroxynandrolone), but was once popular in Europe (Italy and Germany most notably) under the brand name "Steranabol Depot," as it was esterified, dropped in some oil and used as an injectable. (It was also known as "Steranabol Ritardo," which is oxabolone cypionate). Like most steroids with a hydroxyl at carbon 4, oxabolone seems to be a mild aromatase inhibitor and the same is true for OxovarTM/Methoxabol.TM

 Both MOHN and Oxabolone appear pretty much devoid of any progestenic effects (unlike their chemical cousin nandrolone). And like most 4-hydroxylated hormones, OxovarTM/MethoxabolTM and oxabolone are "more anabolic" than their non-4-hydroxylated cousins (nandrolone and 17a-methylnandrolone).  There is a company that does sell a non-17a-methyl version of this stuff; they call it OxabolTM and it is the 17b undecanoate ester of 4,17-dihydroxyestr-4-en-3-one. The company is called Promatrix. I don't know much about the undecanoate version of this stuff, but if you are going to sell an oral prosteroid and you are not going to methylate it at carbon 17, then using the undecanoate ester is the next best thing. 

 

But Back to MOHN...

This stuff is very potent, at least 10 times as potent (anabolic-wise) as is Anavar (oxandrolone). And OxovarTM/MethoxabolTM could easily be used interchangeably with Anavar (oxandrolone) wherever and whenever the latter would normally be used, dose adjustment notwithstanding.  This is awesome news for Anavar lovers because Anavar is notoriously expensive, if not the most expensive anabolic steroid out there. And while the suggested retail price of OxovarTM/MethoxabolTM might seem a bit high in comparison to other prosteroids (methylated or otherwise), when effective dose cost comparisons are made against Anavar (oxandrolone), we find that OxovarTM/MethoxabolTM is a relative bargain. Most people I know who have used Anavar use 20-30 milligrams per day. I am suggesting six to nine milligrams per day for OxovarTM/Methoxabol.TM

  But wait, Bruce. I thought you said OxovarTM/MethoxabolTMwas 10 times more potent than Anavar? This means we should only use two to three milligrams per day. Why do you suggest two to three times that amount? The reason is simple; most users of Anavar would love to use more- 50-60-100 milligrams per day. The fact of the matter is, even the most elite athletes would have problems affording even a 50-milligrams-a-day dose of Anavar. The other thing that really sucks about Anavar is that that just when you really start to see the awesome effects of it (around 30 milligrams per day plus) serious side effects kick in.

A large drug company (I can't mention the name, but you can look it up and find the name and info they gleaned about oxandrolone for yourself) discovered that at about 40 milligrams per day, Anavar is starting to get a little toxic to the liver, even more toxic than equal amounts of Anadrol (oxymetholone). This company did a study of Anavar with people with HIV wasting syndrome and concluded that in calorie-deprived states (people with active HIV often lose their appetites from all the anti-viral drugs they must take just to live), Anavar rocks as an anti-catabolic. Nothing else beats it, which is why Anavar made by BTG is the only officially "approved" steroid sold in America for HIV-related cachexia. In fact, if you're dieting down, trying to cut up and lose the fat, there is not a better steroid than Anavar for keeping the muscle on you while letting the fat drop off.  The same is true for OxovarTM/Methoxabol.TM This is the ultimate cutting prosteroid, folks.

             While Anavar would fucking kick ass and take names if people could tolerate 60-milligram-per-day doses with no serious liver enzyme issues,  OxovarTM/MethoxabolTM(six to nine milligrams per day total) should not cause the serious rise in liver enzyme levels seen in anabolically equivalent doses of Anavar. Sorry kiddies, this stuff cannot be sold in Nevada, Montana or California, so if you live in those three states you are SOL because normethandrolone/MOHN is scheduled at the state level (not federally like norETHandrolone or Nilevar) at C-III (which makes it a "real steroid" in those three states, I guess). Caveat emptor!

 

Reader Question of the Month

I've decided that each month I will choose one or two questions from the letters that come in for me at Muscular Development headquarters. Here's this month's RQOM, which comes from a reader in Canada.  

 
 I am a 38-year-old male, 5'10" at 185 pounds. I work out four to five times per week, and have for the past eight years. I would like to gain five to seven pounds of lean muscle. Presently, I'm only taking whey protein and a multi vitamin. I would like to start using creatine, however, there is so much hype surrounding this product, it's hard to choose which one. I have narrowed it down to three more popular products: Nutrex and Vitagro; SAN and V12 Turbo; and Syntrax and Swole V2. Do you have a preference among these, or is there something better out there? Also, I'd like to know if you've had any feedback from first-time users of products such as 1-Testosterone ester and ether and your Methyldienolone®. Personally, I have never taken a prohormone, but I'm considering it. I am not aware of the possible side effects or benefits. Can you list some pros and cons of taking the supplements?
 

 I'm not a fan of any protein supplements in general. I'd rather get my protein from some eggs, a piece of steak, some tuna fish, anything but a "chocolate shake." But I realize some folks appreciate the convenience (albeit not the taste) of MRPs and protein shakes. And some do not feel they take in enough protein in their diet. So, the whey is okay, it won't hurt, that's for sure.  The multivitamin is also a smart idea. I put all my clients on a quality and cheap-o multi; I prefer whatever generic version of Centrum® you can muster up in your local pharmacy.  It's a cheap insurance policy for good health overall, in my opinion. 

There is a ton of hype surrounding creatine products and all these products seem to "work" to one degree or another. The three you made specific mention of happen to be the "highest tech" of those available and of the three, my preference, hands down, is Nutrex's Vitargo-CGL brand. The SAN and Syntrax stuff both contain a substance called glycocyamine (which is a precursor to creatine actually, also known as guanidoacetic acid) which I am not big on, really. The idea or theory of using glycocyamine (perhaps along with betaine and some other chemicals as methyl donors) to keep the liver cranking out more or extra creatine is a "real stretch" scientifically, in my opinion, and I don't think it is has been conclusively proven to work or not work.

Also, there is a real possibility (depending on what "guru's" advice you subscribe to) that it can actually deplete or reduce creatine stores in muscle cells (the exact opposite of what we want to do). Since the verdict is still out on creatine supplements containing glycocyamine, why bother with them when another company gets around this whole issue by using a proprietary, unique and very effective hexastarch (Vitargo®)? I'd opt for the Nutrex stuff; I know it works and it's the brand of creatine I use personally and put all my clients on when they need creatine supplementation. For the record, I do not make any money from the sale of Vitargo-CGL, nor am I affiliated with the sale of it. I just think it's a kick-ass creatine product. The guys at Nutrex have their shit together with all their products, not just Vitargo-CGL.

The creatine supplementation should help you get the five to seven pounds of mass you're looking for, but if you are in a hurry (or want more than the five to seven pounds you mentioned in your letter) 1-testosterone is indeed one of the better prohormones out there to do the job. Again, Nutrex has a really good one called 1-TU® which is 1-testosterone 17b-undecanoate and it comes in a cool-looking, easy-to-swallow gel cap. I'd suggest three to six caps per day. There are other esters out there being sold attached to prohormone products. Some really don't increase the efficacy nearly as much as Nutrex's undecanoate ester (these would be, in my opinion, the methyl carbonate, ethyl carbonate, propyl carbonate and cypionate esters), or they are about equal in efficacy to Nutrex's undecanoate ester (like the new "hexyl decanoate" ester that Molecular Nutrition uses), but cost more money.

If I was looking for a 1-testosterone product, my opinion is the same as it has been for about eight months now- Nutrex 1-TU®- and remember, the undecanoate ester is the only ester used in oral delivery of any steroids in Europe. If it works for the drug companies, it works for the supplement companies; understand what I am saying? All hormones can have side effects, and many users of 1-testosterone products complain of decreases in libido and some lethargy as the major complaints.  You might experience a little hair loss if you are sensitive to such.

Methyldienolone® is my personal brand name for 17a-methyl-17b-hydroxyestra-4,9(10)dien-3-one, the most potent, milligram for milligram, prosteroid ever conceived, currently being sold through Kilosports and Gaspari Nutrition and by other companies/brand names who chose not to license it from me. (I happen to have a trademark on it and have some personal feelings that everyone should be using my name and licensing it from me, but that is another story for another day). True and real feedback about Methyldienolone® has been stellar to date. It is not the absolute mass builder 17a-methyl-1-testosterone (M1T) is known to be, but it causes a more Winstrol-like or Parabolan-like effect with modest increases in lean tissue and rapid fat loss. I   put together a little table with the names of various "17-alpha alkylated" new high- tech prosteroids, who sells what, and what "real" steroid it most closely resembles. 

 

NAME OF 17-alpha alkylated PROSTEROID

CURRENTLY SOLD BY

EFFECTIVE DOSE FOR AVERAGE 180-200-POUND HEALTHY MALE

"REAL" STEROID  IT MOST CLOSELY RESEMBLES IN EFFECT

Methyldienolone® (17a-methyl-17b-hydroxyestra-4,9(10)dien-3-one)

Gaspari Nutrition, Kilosports, Designer Supplements, others

2-4mg per day, no more than 6mg per day tops; very few side effects reported. Do not stack with any steroid, legal or otherwise, that will aromatize into an estrogen or take with an anti-estrogen. Methyldienolone is almost devoid of estrogenic effects but there is a slight chance of progestenic effects in some individuals.

Winstrol or Parabolan

Methyl-1-Test (various brands of 17a-methyl-1-testosterone)

Legal Gear, VPX, SAN, others

5mg per day, no more than 10mg per day for very experienced users - tends to cause serious headaches, lethargy, and has been at least linked to high blood pressure and epistaxis (nosebleeds); causes rapid gains if you can tolerate the side effects.

Anadrol, high dose Dianabol.

OxoVarTM (17a-methyl-3-oxo-19-norandrostene-4,17-diol)

Kilosports, Gaspari Nutrition (these are the only two selling this stuff to date in tabs/caps); Designer Supplements (in liquid drops only).

6-9mg per day.  Users describe very rapid gains in strength, hardening and vascularity with great concomitant fat loss. Not as fantastic a mass builder as some of the others; expect 50-70% the size you'd get with others; this is more of a "strength" prosteroid and the newest one to hit the market. Very few (if any) side effects.

High-dose Anavar

M1,4AD (aka, 17a-methyl-boldenol)

Unknown if sold in caps or tabs, only have seen raw powder for sale.

20-60mg per day, this is essentially "legal" dbol and is a direct precursor to it. You must take with an anti-estrogen or you seriously risk getting gyno and shutting down your HPTA

Almost identical to Dianabol

M4-AD (17a-methyl-4-androstenediol)

VPX

30-60mg per day. Prosteroid to methyltestosterone. Does not aromatize (or does not appear to).  This was the first methylated prosteroid I [Bruce Kneller] came out with over a year ago; a little on the crude and ineffective side in light of newer items found in this table.

Very similar to methyltestosterone (good for increasing aggression, energy and some small gains in mass and strength).

M5-AA (17a-methyl-5-androstanediol)

VPX, some smaller companies.

20-40mg per day, prosteroid to DHT, causes great strength gains but can cause rapid hair loss in people susceptible to male pattern baldness. This was the second methylated prohormone I [Bruce Kneller] developed about nine months ago.  Stacks well with Methyldienolone®

Stenbolone, DHT